The calcium of bone is in a constant exchange with the calcium of plasma. The major fraction (99%) of calcium is in the skeletal structure primarily as hydroxyapatite, Ca 10(PO 4) 6(OH) 2 small amounts of calcium carbonate and amorphous calcium phosphates are also present. Also, calcium helps to regulate the release and storage of neurotransmitters and hormones, the uptake and binding of amino acids, absorption of vitamin B 12, and gastrin secretion. It plays a role in normal cardiac function, renal function, respiration, blood coagulation, and cell membrane and capillary permeability. Mechanism of actionĬalcium is essential for the functional integrity of the nervous, muscular, and skeletal systems. This agent may also be chemopreventive for colon and other cancers. An element or mineral necessary for normal nerve, muscle, and cardiac function, calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally. Type Small Molecule Groups Approved, Vet approved StructureĬalcium Gluconate is the gluconate salt of calcium. Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium gluconate.Įach 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). Each mL contains: Calcium gluconate 94 mg calcium saccharate (tetrahydrate) 4.5 mg water for injection q.s. It can also be taken by mouth but is not recommended by injection into a muscle.Ĭalcium Gluconate Injection, USP is a sterile, nonpyrogenic supersaturated solution of calcium gluconate for intravenous use only. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. ![]() ![]() Generic Name Calcium gluconate DrugBank Accession Number DB11126 BackgroundĬalcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. ![]() Calcium gluconate is an ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning.
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